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Science 12 July 1968:
Vol. 161. no. 3837, pp. 180 - 181
DOI: 10.1126/science.161.3837.180
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Articles

Aspirin: Action on Receptor in the Tooth

Donald Scott Jr. 1

1 Department of Physiology, School of Medicine, University of Pennsylvania, Philadelphia

Impulse frequency recorded from dentinal receptors in the cat's tooth provided an indication of sensory excitation. Topical application of aspirin to the dentin promptly inhibited both steady-state discharge and response to a brief heat stimulus. When the drug was washed out, the initial excitability was restored in 15 minutes.


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