Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 12 July 1968:
Vol. 161. no. 3837, pp. 170 - 171
DOI: 10.1126/science.161.3837.170
Prev | Table of Contents | Next

Articles

Actomyosin-Like Protein Isolated from Mammalian Brain

S. Puszkin 1, S. Berl 1, Elena Puszkin 2, and D. D. Clarke 3

1 Columbia University, College of Physicians and Surgeneous, New York 10032
2 Mount Sinai School of Medicine, New York
3 Fordham University, Bronx, New York

A protein with characteristics similar to actomyosin has been isolated from whole brain of rat and cat. It is soluble in 0.6 molar potassium chloride and insoluble in 0.1 molar potassium chloride. It superprecipitates with magnesium ions and adenosine triphosphate. It has adenosine triphosphatase activity stimulated by either magnesium or calcium ions. Both superprecipitation and adenosine triphosphatase activity are inhibited by p-chloromercuribenzoate and Mersalyl but not by ouabain.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Molecular Genetic Classification of Central Nervous System Malformations.
H. B. Sarnat (2000)
J Child Neurol 15, 675-687
   Abstract »    PDF »
A conventional myosin motor drives neurite outgrowth.
S. R. Wylie, P.-j. Wu, H. Patel, and P. D. Chantler (1998)
PNAS 95, 12967-12972
   Abstract »    Full Text »    PDF »
Interaction of brain synaptic vesicles induced by endogenous Ca2+ -dependent phospholipase A2.
N Moskowitz, W Schook, and S Puszkin (1982)
Science 216, 305-307
   Abstract »    PDF »
Axonal Transport of Vesicles Carrying [3H]Serotonin in the Metacerebral Neuron of Aplysia californica.
J. H. Schwartz, J. E. Goldman, R. T. Ambron, and D. J. Goldberg (1976)
Cold Spring Harb Symp Quant Biol 40, 83-92
   Abstract »    PDF »
Actomyosin-Like Protein in Brain: Actomyosin-like protein may function in the release of transmitter material at synaptic endings.
S. Berl, S. Puszkin, and W. J. Nicklas (1973)
Science 179, 441-446
   PDF »
Microfilaments in Cellular and Developmental Processes.
N. K. Wessells, B. S. Spooner, J. F. Ash, M. O. Bradley, M. A. Luduena, E. L. Taylor, J. T. Wrenn, and K. M. Yamada (1971)
Science 171, 135-143
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)