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Science 5 July 1968:
Vol. 161. no. 3836, p. 56
DOI: 10.1126/science.161.3836.56
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Articles

Falciparum Malaria Transmissible from Monkey to Man by Mosquito Bite

Peter G. Contacos 1 and William E. Collins 1

1 National Institute of Allergy and Infectious Diseases, P.O. Box 80190, Chamblee, Georgia 30005

Anopheles freeborni mosquitoes were infected by feeding on a New World monkey, Aotus trivirgatus, infected with the Malayan IV strain of Plasmodium falciparum. After a normal incubation period, the infection was passed to a human volunteer through the bites of these mosquitoes, demonstrating for the first time the practicability of using a simian host as a donor for the infection of mosquitoes with this species of human malarial parasites.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Adaptation of a Multi-drug Resistant Strain of Plasmodium falciparum from Peru to Aotus lemurinus griseimembra, A. nancymaae, and A. vociferans Monkeys.
W. E. Collins, J. S. Sullivan, P. Hall, T. K. Ruebush II, A. Williams, K. K. Grady, A. Bounngaseng, D. Nace, T. Williams, C. Huber, et al. (2007)
Am J Trop Med Hyg 77, 261-265
   Abstract »    Full Text »    PDF »
Plasmodium malariae: Transmission from Monkey to Man by Mosquito Bite.
P. G. Contacos and W. E. Collins (1969)
Science 165, 918-919
   Abstract »    PDF »
Malaria and Victory in Vietnam.
W. Modell (1968)
Science 162, 1346-1352
   PDF »


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