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Science 28 June 1968:
Vol. 160. no. 3835, pp. 1462 - 1463
DOI: 10.1126/science.160.3835.1462
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Articles

Lectins in Extracts of Certain Polygonaceae Seed Precipitate Animal and Human Serums

Ernest B. Hanan 1 and James W. Spindler 2

1 Laboratory, Burge-Protestant Hospital, Springfield, Missouri
2 2949 Laclede Avenue, St. Louis, Missouri 63103

Seeds of four species of Polygonaceae were tested for lectins that precipitate human and animal serums. Rumex crispus, Polygonum convolvulus, and Polygonum pennsylvanicum developed specific precipitate bands on double diffusion on agar gel plates. These bands were enhanced and increased in number when extracts were tested against serums from patients with certain diseases. When tested against lyophilized serum, no precipitate bands developed. The active substance cannot be dialyzed through cellulose membrane against running tap water for 16 hours, and it is heat stable. Extracts from Fagopyrum esculentum developed no precipitate bands.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)