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Science 17 November 1967:
Vol. 158. no. 3803, pp. 922 - 924
DOI: 10.1126/science.158.3803.922
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Articles

Carotenoid Biosynthesis in Rhodospirillum rubrum: Effect of Pteridine Inhibitor

N. A. Nugent 1 and R. C. Fuller 1

1 Department of Microbiology, Dartmouth Medical School, Hanover, New Hampshire

A known inhibitor of pteridine utilization (4-phenoxy,2,6-diamino pyridine) blocks the synthesis of colored carotenoids in the photosynthetic bacterium Rhodospirillum rubrum. In many ways the effect is similar to the inhibition of the synthesis of colored carotenoids by diphenylamine. This inhibition is probably independent of other effects of pteridine on photosynthetic electron transport since it is not as readily reversible as the total inhibition of photosynthetic activity by pteridine analogs.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)