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Science 27 October 1967:
Vol. 158. no. 3800, pp. 512 - 514
DOI: 10.1126/science.158.3800.512
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Articles

Antigenic Competition: Cellular or Humoral

Jevrosima Radovich 1 and David W. Talmage 1

1 Department of Microbiology, University of Colorado Medical Center, Denver

The injection of one antigen into mice inhibited the response to a second when 1 to 10 days separated the two injections. When the same type of inhibition was attempted in ggr-irradiated mice reconstituted with normal spleen cells, the inhibition was greater in mice receiving 50 million spleen cells than in those receiving 10 million. The results are interpreted as favoring a humoral mechanism of inhibition.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Antigen Competition: Antigens Compete for a Cell Occurring with Limited Frequency.
J. F. Albright, T. F. Omer, and J. W. Deitchman (1970)
Science 167, 196-198
   Abstract »    PDF »
Apparent Production of Two Types of Antibodies by a Single Cell.
J. G. Michael and R. Marcus (1968)
Science 159, 1247-1249
   Abstract »    PDF »


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