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Science 22 September 1967:
Vol. 157. no. 3795, pp. 1461 - 1463
DOI: 10.1126/science.157.3795.1461
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Articles

Serotonin Release from Brain Slices by Electrical Stimulation: Regional Differences and Effect of LSD

Thomas N. Chase 1, George R. Breese 1, and Irwin J. Kopin 1

1 National Institutes of Health, Bethesda, Maryland 20014

Slices of rat brain which had accumulated tritiated serotonin either in vivo or in vitro were superfused and electrically stimulated. There occurred a marked release of the exogenous amine and, to a lesser extent, its deaminated metabolites, which varied with the region of brain tested and was inhibited by lysergic acid diethylamide.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Dopamine: Stimulation-Induced Release from Central Neurons.
K. Y. Ng, T. N. Chase, R. W. Colburn, and I. J. Kopin (1971)
Science 172, 487-489
   Abstract »    PDF »
Evoked Release of Norepinephrine and Serotonin from Brain Slices: Inhibition by Lithium.
R. I. Katz, T. N. Chase, and I. J. Kopin (1968)
Science 162, 466-467
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)