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Science 1 September 1967:
Vol. 157. no. 3792, pp. 1070 - 1072
DOI: 10.1126/science.157.3792.1070
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Articles

Gene Activation without Histone Acetylation in Drosophila melanogaster

Erik G. Ellgaard 1

1 Department of Zoology, University of Iowa, Iowa City

Chromosomal puffing, generally believed to represent gene activation in Drosophila, was induced in the presence of radioactively labeled acetate. There is no preferential uptake of these labeled molecules in regions of gene activation. It is concluded that the acetylation of histones does not play a general role in the regulation of RNA synthesis in Drosophila melanogaster.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Puffing and Histone Acetylation in Polytene Chromosomes.
U. Clever and E. G. Ellgaard (1970)
Science 169, 373-374
   Abstract »    PDF »
Histone Acetylation in Insect Chromosomes.
V. G. Allfrey, B. G. T. Pogo, V. C. Littau, E. L. Gershey, and A. E. Mirsky (1968)
Science 159, 314-316
   Abstract »    PDF »


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