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Science 21 July 1967:
Vol. 157. no. 3786, pp. 319 - 321
DOI: 10.1126/science.157.3786.319
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Articles

Genetic Recombination in Escherichia coli: Clone Heterogeneity and the Kinetics of Segregation

Thomas H. Wood 1

1 Department of Physics, University of Pennsylvania, Philadelphia

Several recombinant types may be produced from a single Escherichia coli zygote when the donor parent is Hfr-Hayes and segregation is delayed; usually only one type is produced with Hfr-Cavalli. Statistical experiments confirm well-known pedigree analyses by micromanipulation and suggest that DNA synthesis is required before final genetic integration.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)