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Science 30 June 1967:
Vol. 156. no. 3783, p. 1762
DOI: 10.1126/science.156.3783.1762-a
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Articles

Endrin Resistance in the Pine Mouse

Ryland E. Webb 1 and Frank Horsfall Jr. 1

1 Department of Biochemistry and Nutrition and Department of Horticulture, Virginia Polytechnic Institute, Blacksburg 24061

Wild pine mice with a history of treatment with endrin exhibited a 12-fold greater tolerance to the pesticide than did mice having no history of endrin treatment. A genetic basis for the resistance would be expected, in view of the fact that the resistant mice had been exposed to endrin for 11 years. However, sublethal dosages conferred a degree of resistance on both mouse populations; this indicates the possibility of an inducible resistance.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)