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Science 30 June 1967:
Vol. 156. no. 3783, pp. 1746 - 1748
DOI: 10.1126/science.156.3783.1746
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Articles

Ring D Chromosome: A Second Case Associated with Anomalous Haptoglobin Inheritance

Gerald E. Bloom 1, Park S. Gerald 1, and Leonard E. Reisman 2

1 Clinical Genetics Division, Children's Hospital Medical Center, and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts
2 University of Louisville, Louisville, Kentucky

A second child with a ring D chromosome and anomalous inheritance of haptoglobin has been identified. Autoradiographic studies of peripheral lymphocytes from this child and of those from the previously described patient indicate that the ring in each is derived from chromosome No. 13. These findings are evidence that the locus for the haptoglobin alpha-chain is situated on one end of chromosome No. 13.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Familial Deletion of the Short Arm of the D1-Chromosome (46, XX, 13 p-) Not Associated with Loss of Haptoglobin or Catalase Activity.
C. E. Parker, R. Koch, J. Mavalwala, A. Derencsenyi, and A. Hatashita (1969)
Clinical Pediatrics 8, 453-458
   Abstract »    PDF »
IgA Deficiency Associated With Partial Deletion of Chromosome 18.
M. Feingold, R. S. Schwartz, L. Atkins, R. Anderson, C. S. Bartsocas, D. L. Page, and J. W. Littlefield (1969)
Arch Pediatr Adolesc Med 117, 129-136
   Abstract »    PDF »
Haptoglobin and Catalase Loci in Man: Possible Genetic Linkage.
W. E. Nance, J. E. Empson, T. W. Bennett, and L. Larson (1968)
Science 160, 1230-1231
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)