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Science 19 May 1967:
Vol. 156. no. 3777, pp. 961 - 963
DOI: 10.1126/science.156.3777.961
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Articles

Field Ion Microscopical Imaging of Biomolecules

Erwin W. Müller 1 and Klaus D. Rendulic 1

1 Department of Physics, Pennsylvania State University, University Park 16802

specimen molecules are protected from field desorption by embedding them in a platinum matrix, with the use of electrolytic codeposition on tungsten tips. High-resolution helium ion images are obtaind when the biomolecules are exposed during gradual removal of surface layers by controlled field evaporation. Structured images of individual molecules of coenzyme I and vitamin B12are seen.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)