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Science 5 May 1967:
Vol. 156. no. 3775, pp. 659 - 661
DOI: 10.1126/science.156.3775.659
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Articles

Human Fibroblasts Infected with Rubella Virus Produce a Growth Inhibitor

Stanley A. Plotkin 1 and Antti Vaheri 1

1 The Wistar Institute, Philadelphia, Pennsylvania

A protein that inhibited mitosis of normal human diploid cells was demonstrated in extracts of WI-38 cells that were infected with rubella virus and that had gone into mitotic arrest subsequent to infection. A possible mechanism for the pathogenesis of the rubella syndrome is suggested.


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Rubella Virus Replication and Links to Teratogenicity.
J.-Y. Lee and D. S. Bowden (2000)
Clin. Microbiol. Rev. 13, 571-587
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Routes of Fetal Infection and Mechanisms of Fetal Damage.
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Arch Pediatr Adolesc Med 129, 444-449
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The Pathologic Manifestations: f Intrauterine Rubella Infection.
J. R. Esterly and E. H. Oppenheimer (1973)
Arch Otolaryngol Head Neck Surg 98, 246-248
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Effects of Rubella Virus Infection on the Division of Human Cells.
A. Boue and J. G. Boue (1969)
Arch Pediatr Adolesc Med 118, 45-48
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Histopathology of Gestational Rubella.
S. G. Driscoll (1969)
Arch Pediatr Adolesc Med 118, 49-53
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