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Science 3 February 1967:
Vol. 155. no. 3762, pp. 573 - 575
DOI: 10.1126/science.155.3762.573

Articles

Nitrate Ions: Potentiation of Increased Permeability to Sugar Associated with Muscle Contraction

John O. Holloszy 1 and H. T. Narahara 1

1 Department of Biological Chemistry, Washington University School of Medicine, St. Louis, Missouri 63110

Nitrate ions potentiate twitch tension and enhance the increase in permeability to sugar which occurs in electrically stimulated frog sartorius muscles. However, the potentiating effect of nitrate ions on permeability is not dependent upon an increase in twitch tension. The possible relation of changes in permeability to alterations of the concentration of calcium ions in the cell is discussed.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)