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Science 27 January 1967:
Vol. 155. no. 3761, pp. 469 - 470
DOI: 10.1126/science.155.3761.469
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Articles

Nuclear-Cytoplasmic Interaction in DNA Synthesis

David M. Prescott 1 and Lester Goldstein 2

1 Institute for Developmental Biology, University of Colorado, Boulder
2 Department of Biology, University of Pennsylvania, Philadelphia

In Amoeba proteus the transplantation of a nucleus engaged in DNA synthesis into a G2-phase (after DNA synthesis) cell results in inhibition of such synthesis. When the nucleus of a G2 cell is transplanted into an S-phase (period of DNA synthesis) cell, such a nucleus may begin to synthesize DNA.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)