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Science 20 January 1967:
Vol. 155. no. 3760, pp. 341 - 342
DOI: 10.1126/science.155.3760.341
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Articles

Seizure Discharges Evoked in Vitro in Thin Section from Guinea Pig Hippocampus

Chosaburo Yamamoto 1 and Nobufumi Kawai 1

1 Behavior Research Institute, University of Gunma Medical School, Maebashi, Japan

A thin section prepared from guinea pig hippocampus produced, in chloride-free medium, a train of seizure discharges in response to a single shock applied to the section. Generation of these discharges was ascribed to the lack of inhibitory processes in an absence of chloride ion.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Calcium Waves Precede Electrophysiological Changes of Spreading Depression in Hippocampal Organ Cultures.
P. E. Kunkler and R. P. Kraig (1998)
J. Neurosci. 18, 3416-3425
   Abstract »    Full Text »    PDF »
Reducing Extracellular Cl- Suppresses Dihydropyridine-Sensitive Ca2+ Currents and Synaptic Transmission in Amphibian Photoreceptors.
W. B. Thoreson, R. Nitzan, and R. F. Miller (1997)
J Neurophysiol 77, 2175-2190
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)