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Science 2 December 1966:
Vol. 154. no. 3753, pp. 1197 - 1199
DOI: 10.1126/science.154.3753.1197
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Articles

Evidence from Cultured Leucocytes of Blood Cell Chimerism in Ex-Parabiotic Frogs

E. Peter Volpe 1 and Bryan M. Gebhardt 1

1 Department of Biology, Tulane University, New Orleans, Louisiana

Postmetamorphic diploid and triploid frogs that had earlier been joined in parabiotic union from embryonic life until metamorphosis were each found to be chimeric with respect to their blood cells, as revealed in chromosome preparations of cultured leucocytes. Blood cells precursorsmost likely were interchanged when the ex-parabionts shared a common circulation in embryonic life,and the exchanged precursor cells apparently homed in the hematopoietic tissues of the hosts. The tolerance which exparabiotic pairs of frogs exhibit toward grafts of each other's skin is attributable to the blood cell chimerism.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Somatic Cell Mating and Segregation in Chimeric Frogs.
E. P. Volpe and E. M. Earley (1970)
Science 168, 850-852
   Abstract »    PDF »
Germ Cell Chimerism: Absence in Parabiotic Frogs.
E. P. Volpe and S. Curtis (1968)
Science 160, 328-329
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)