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Science 25 November 1966:
Vol. 154. no. 3752, pp. 1034 - 1035
DOI: 10.1126/science.154.3752.1034

Articles

Multiple Gene Loci for the Monomeric Hemoglobin of the Hagfish (Eptatretus stoutii)

Susumu Ohno 1 and Martin Morrison 1

1 Departments of Biology and Biochemistry, City of Hope Medical Center, Duarte, California

The fact that members of the subclass Cyclotomata possess monomeric hemoglobin molecules has been known for some time. Electrophoresis of hemolysates from 12 hagfish (Eptatretus stoutii) revealed five hemoglobin phenotypes with four to six distinct zones of hemoglobin. Each zone is believed to represent a monomer containing one heme group on a single polypeptide chain with a molecular weight of approximately 18,000. It is postulated that these monomers are controlled by genes at four loci.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Genetic Control of Lactate Dehydrogenase Formation in the Hagfish Eptatretus stoutii.
S. Ohno, J. Klein, J. Poole, C. Harris, A. Destree, and M. Morrison (1967)
Science 156, 96-98
   Abstract »    PDF »
Hagfish Hemoglobins. STRUCTURE, FUNCTION, AND OXYGEN-LINKED ASSOCIATION.
A. Fago, L. Giangiacomo, R. D'Avino, V. Carratore, M. Romano, A. Boffi, and E. Chiancone (2001)
J. Biol. Chem. 276, 27415-27423
   Abstract »    Full Text »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)