Rate of Movement and Redistribution of Stainable Neurosecretory Granules in Hypothalamic Neurons
Andrzej Jasinski 1,
Aubrey Gorbman 2, and
Toshiaki J. Harat 2
1 Department of Zoology, University of Washington, SeaittleHoyer Department of Comparative Anatomy, Jagiellonian University, 50 Krupnicza Street, Cracow, Poland.
2 Department of Zoology, University of Washington, Seaittle
Electrical stimulation of the olfactory tract of goldfish for one minute can deplete completely the stainable neurosecretory granules from cells of the preoptic nucleus as well as from their axons. Thus, in stimulated neurons secretory granules appear to move toward the neurohemal point of discharge at a rate of about 2 millimeters per minuite. Reaccumutlation of neurosecretory granules in depleted neurons to approximately normal numbers requires about 1 to 1.5 hours. Histological evidence indicates that, during the period of reaccumulation, granules move out of the perikaryon until normal granulation in the axons is achieved; finally, granulation of the perikaryon is restored.
