Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 4 November 1966:
Vol. 154. no. 3749, pp. 676 - 677
DOI: 10.1126/science.154.3749.676
Prev | Table of Contents | Next

Articles

Passive Sensitization in vitro: Effect of Antibody Concentration on the Lag Period and Velocity

George A. Feigen 1 and Christen B. Nielsen 1

1 Department of Physiology, Stanford University, Stanford, California 94305; Division of Neurology, Veterans Administration Hospital, Palo Alto, California 94304

Strips of guinea pig ileum were sensitized in vitro in various concen trations of rabbit antibody prepared against ovalbumin. The dependence of the first-order velocity constants upon antibody concentration was hyperbolic. The limiting velocity constant was 0.0097 per minute, and the antibody concentration giving half the limiting velocity was 0.0035 milligrams per milliliter. The lag period varied inversely with the logarithm of the antibody concentration.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)