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Science 28 October 1966:
Vol. 154. no. 3748, pp. 535 - 537
DOI: 10.1126/science.154.3748.535
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Articles

Polymorphism of Heavy-Chain Genes in Immunoglobulins of Wild Mice

Rose Lieberman 1 and Michael Potter 2

1 National Institute of Allergy and Infectious Diseases, Bethesda, Maryland
2 National Cancer Institute

The serums of 123 wild mice from six different geographic locations in the United States contain five of the six known heavy-chain antigenic determinants that have been identified in immunoglobulin of inbred laboratory strains of mice. On the basis of the distribution of determinants in inbred strains,44 of the mice were judged to be heterozygotes of various combinations and two had combinations of determinants that were unusual and could only have occurred in laboratory inbred mice by recombination.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Genetic Studies of Immunoglobulins in Mice.
M. Potter and R. Lieberman (1967)
Cold Spring Harb Symp Quant Biol 32, 187-202
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Science. ISSN 0036-8075 (print), 1095-9203 (online)