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Science 28 October 1966:
Vol. 154. no. 3748, pp. 522 - 523
DOI: 10.1126/science.154.3748.522
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Articles

Reovirus-Specific Polyribosomes in Infected L-Cells

L. Prevec 1 and A. F. Graham 1

1 Wistar Institute, Philadelphia, Pennsylvania

Polyribosomes were isolated from reovirus-infected L-cells. Virusinduced RNA isolated from these polyribosomes was single-stranded, heterogeneous in size, and capable of extensive hybridization with viral double-stranded RNA. Reovirus RNA, therefore, specifies in infected cells the formation of a single-stranded messenger RNA for virus-specific protein synthesis.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)