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Science 30 September 1966:
Vol. 153. no. 3744, pp. 1664 - 1666
DOI: 10.1126/science.153.3744.1664
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Articles

Albumin Naskapi: A New Variant of Serum Albumin

Liisa Melartin 1 and B. S. Blumberg 2

1 Department of Medical Microbiology, University of Turku, Turku, Finland
2 Institute for Cancer Research, 7701 Burholme Avenue, Fox Chase, Philadelphia, Pennsylvania

An apparently new Variant of human serum albumin, albumin Naskapi, has been found in high frequency in the Naskapi Indians of Quebec and, in lower frequency,in other North American Indians.The family and population data of the albumin are consistent with its inheritance as a simple autosomal trait Controlled by a gene designated Al Naskapi. This gene is allelic with the gene AlA which controls the common albumin.Both homozygotes and heterozygotes have been distinguished. This is the first report of a homozygote for an albumin Variant.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Haplotypic Background of a Private Allele at High Frequency in the Americas.
K. B. Schroeder, M. Jakobsson, M. H. Crawford, T. G. Schurr, S. M. Boca, D. F. Conrad, R. Y. Tito, L. P. Osipova, L. A. Tarskaia, S. I. Zhadanov, et al. (2009)
Mol. Biol. Evol. 26, 995-1016
   Abstract »    Full Text »    PDF »
Reduced warfarin binding of albumin variants.
G Wilding, E. Blumberg, and E. Vesell (1977)
Science 195, 991-994
   Abstract »    PDF »
Alloalbuminemia: Albumin Naskapi in Indians of the Ungava.
B. S. Blumberg, J. R. Martin, and L. Melartin (1968)
JAMA 203, 180-185
   Abstract »    PDF »
Autosomal Linkage between the Albumin and Gc Loci in Humans.
E. Kaarsalo, L. Melartin, and B. S. Blumberg (1967)
Science 158, 123-125
   Abstract »    PDF »


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