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Science 23 September 1966:
Vol. 153. no. 3743, pp. 1543 - 1544
DOI: 10.1126/science.153.3743.1543

Articles

Ascending and Descending Cholinergic Fibers in Cat Spinal Cord: Histochemical Evidence

D. G. Gwyn 1 and J. H. Wolstencroft 1

1 Department of Anatomy and Medical Research Council, Neuropharmacology Research Unit, University of Birmingham, Birmingham, England

The distribution of fibers staining for cholinesterase in the spinal cord of the cat was examined after hemisection at the level of the third cervical segment (C3), of the tenth thoracic segment (Ti 0), or of the first lumbar segment (LI). An accumulation of cholinesterase was found in many fibers of the cord both rostral and caudal to the lesion, the distribution being different in the two regions. These experiments indicate that there are ascending and descending cholinergic fibers in cat spinal cord.





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Science. ISSN 0036-8075 (print), 1095-9203 (online)