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Science 3 June 1966:
Vol. 152. no. 3727, pp. 1376 - 1377
DOI: 10.1126/science.152.3727.1376
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Articles

Mammary Tumor Inhibition and Lung Adenoma Induction by Isonicotinic Acid Hydrazide

Bela Toth 1 and Philippe Shubik 1

1 Division of Oncology, Chicago Medical School, Chicago, Illinois

The occurrence of manomary adenocarcinonmas in C3H mice is largely inhibited by prolonged admninistration of 0.1 percent isonicotinic acid hydrazide in drinking water. At the same time that this compound produtced the inhibitory action, it also increased the incidence of pulmonary adenomas.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)