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Science 27 May 1966:
Vol. 152. no. 3726, pp. 1256 - 1257
DOI: 10.1126/science.152.3726.1256

Articles

Starch-Gel Electrophoresis of Human Tissue Enzymes Which Hydrolyze L-Leucyl-beta-Naphthylamide

Edgar E. Smith 1 and Alexander M. Rutenburg 1

1 Departments of Surgery, Beth Israel Hospital, and Harvard Medical School, Boston, Massachusetts

Electrophoretically distinct formls of the enzyme or enzymes which catalyze the hydrolysis of L-leucyl-beta-naphthylamide were demonstrated in various human tissues. There were characteristic patterns for different tissues. Unlike the enzymes found in normnal serum, some tissue-specific enzymes were unaffected or activated L-methionine.





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Science. ISSN 0036-8075 (print), 1095-9203 (online)