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Science 20 May 1966:
Vol. 152. no. 3725, pp. 1082 - 1083
DOI: 10.1126/science.152.3725.1082
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Articles

Virus-induced Murine Leukemia: Its Inhibition and Suppression by Serum Containing Erythropoietin

Philip G. Stansly 1 and Pauline E. Schiop 1

1 Detroit Institute of Cancer Research, Detroit, Michigan, and Department of Microbiology, School of Medicine, Wayne State University, Detroit

Mice infected at 2 days of age with a virus that induces reticulum cell sarcoma and myeloerythroleukemia were treated with erythropoietin-containing serum obtained from rabbits that had been treated with acetylphenylhydrazine. A marked inhibition of tumor induction occurred, particularly in females, when treatment was begun early. Delayed treatment resulted in instances of regression of overt neoplasia.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)