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Science 25 March 1966:
Vol. 151. no. 3717, pp. 1558 - 1560
DOI: 10.1126/science.151.3717.1558
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Articles

Dreaming Sleep in Man: Changes in Urine Volume and Osmolality

A. J. Mandell 1, B. Chaffey 1, P. Brill 1, M. P. Mandell 1, J. Rodnick 1, R. T. Rubin 1, and R. Sheff 1

1 Departments of Psychiatry and Urology, University of California, Center for the Health Sciences, Los Angeles, and Wadsworth Veterans Administration Hospital, Los Angeles

Epochs of dreaming sleep, as measured by rapid eye movements, consistently correlated with biphasic change in urine volume and osmolality in catheterized human subjects. Marked decrease in volumne and increase in oslnolality were followed by a hypotonic diuresis.


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