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Science 18 March 1966:
Vol. 151. no. 3716, pp. 1406 - 1408
DOI: 10.1126/science.151.3716.1406
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Articles

Hemoglobin Sphakiá: A Delta-Chain Variant of Hemoglobin A2 from Crete

R. T. Jones 1, B. Brimhall 1, E. R. Huehns 2, and N. A. Barnicot 3

1 Division of Experimental Medicine and Department of Biochemistry, University of Oregon Medical School, Portland
2 Medical Research Council Group in Hemolytic Anemia, University College Hospital Medical School, London
3 Department of Anthropology, University College, London

A new variant of the normal minor component Hb A2 has been detected in a family that lives in Sphakiá, Crete. Chemical studies of this abnormal hemoglobin, designated Hb A2 dgr Sphakiá, indicates a substitution of the histidyl residue number two of the dgr-chain by an arginyl residue.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)