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Science 14 January 1966:
Vol. 151. no. 3707, pp. 205 - 206
DOI: 10.1126/science.151.3707.205

Articles

Spontaneous Mutation Rates at Five Coat-Color Loci in Mice

Gunther Schlager 1 and Margaret M. Dickie 1

1 Jackson Laboratory, Bar Harbor, Maine 04609

Examination of 1.5 million mice yielded natural mutation rates estimnated from 5.2 million gene reproductions at five specific coat-color loci. The average rates were 11.1 x 10-6 for forward mutations and 2.7 x 10-6 for reverse mutations. Differences between the frequencies of mutations at the individual loci were evident.





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Science. ISSN 0036-8075 (print), 1095-9203 (online)