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Science 31 December 1965:
Vol. 150. no. 3705, pp. 1827 - 1828
DOI: 10.1126/science.150.3705.1827
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Articles

Beta-Solamarine: Tumor Inhibitor Isolated from Solanum dulcamara

S. Morris Kupchan 1, Stanley J. Barboutis 1, John R. Knox 1, and Cesar A. Lau Cam 1

1 Department of Pharmaceutical Chemistry, University of Wisconsin, Madison

An alcoholic extract of Solanum dulcamara L., a plant widely used in folk medicine for treating cancers and warts, shows tumor-inhibitory activity against Sarcoma 180 in mice. Systematic fractionation of the extract has led to isolation and characterization of beta-solamarine as an active principle.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)