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Science 3 December 1965:
Vol. 150. no. 3701, pp. 1307 - 1309
DOI: 10.1126/science.150.3701.1307
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Articles

Submaxillary Gland of Mouse: Effects of a Fraction on Tissues of Mesodermal Origin in vitro

D. Gandini Attardi 1, R. Levi-Montalcini 1, B. S. Wenger 1, and P. U. Angeletti 2

1 Department of Zoology, Washington University, St. Louis, Missouri
2 Istituto Superiore di Sanitá, Viale Regina Elena, 299, Rome

A macromolecular fraction from mouse salivary glands markedly enhances growth of mesenchymal tissues in vitro. The same fraction causes dedifferentiation of tissues of mesodermal origin, such as muscle and cartilage. Dedifferentiated tissues do not divide but survive in good condition, while controls in the same cultural media undergo regressive changes.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Biochemical and Morphological Studies of Rat Submandibular Gland: II. Partial Purification of Proteins from Granule-Rich Fraction.
S.G. Chakrabarti, C.T. Hanks, and S.P. Johnson (1975)
Journal of Dental Research 54, 948-959
   Abstract »    PDF »
Effects of Whole Human Saliva and the Extracts of Bovine Parotid and Submaxillary Glands on Serum Calcium Levels in Mice.
R. M. Stringham JR, C. A. Bonilla, and I. M. Lytle (1967)
Journal of Dental Research 46, 1032-1035
   PDF »
Submaxillary Gland of Mouse: Properties of a Purified Protein Affecting Muscle Tissue in vitro.
D. G. Attardi, M. J. Schlesinger, and S. Schlesinger (1967)
Science 156, 1253-1255
   Abstract »    PDF »


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