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Science 29 October 1965:
Vol. 150. no. 3696, pp. 622 - 626
DOI: 10.1126/science.150.3696.622
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Articles

Template Activity of RNA from Antibody-Producing Tissues

Bernard Mach 1 and Pierre Vassalli 2

1 Laboratory of Biochemical Genetics, Rockefeller Institute, New York
2 Department of Pathology, New York University School of Medicine, New York

An RNA fraction, which represents a small percentage of cellular RNA and which has the characteristics of nuclear messenger RNA, has been isolated from the spleen and lymph nodes of immunized rats by successive phenol extractions of these tissues at increasing temperatures. This fraction increased the amount of protein synthesized in a cell-free extract of Escherichia coli as much as 35 times and directed the synthesis of proteins different from those of E. coli.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Biosynthesis of Immunoglobulin in a Cell-Free System.
B. Mach, H. Koblet, and D. Gros (1967)
Cold Spring Harb Symp Quant Biol 32, 269-275
   Abstract »    PDF »
Biosynthesis of Gamma Globulin: Studies in a Cell-Free System.
K. H. Stenzel and A. L. Rubin (1966)
Science 153, 537-539
   Abstract »    PDF »
Synthesis of Nonribosomal RNA by Lymphocytes: A Response to Phytohemagglutinin Treatment.
H. L. Cooper and A. D. Rubin (1966)
Science 152, 516-518
   Abstract »    PDF »


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