Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 10 September 1965:
Vol. 149. no. 3689, pp. 1249 - 1251
DOI: 10.1126/science.149.3689.1249
Prev | Table of Contents | Next

Articles

Inhibitory Oxidation Products of Indole-3-Acetic Acid: Enzymic Formation and Detoxification by Pea Seedlings

C. C. Still 1, Carol C. Olivier 1, and H. S. Moyed 1

1 Department of Microbiology, School of Medicine, University of Southern California, Los Angeles 90033

Extracts of etiolated pea seedlings oxidize indole-3-acetic acid, a plant auxin, to 3-hydroxymethyloxindole. At physiological pH this compound is dehydrated to 3-methyleneoxindole, a highly reactive sulfhydryl reagent and inhibitor of cell growth. 3-Methlyeneoxindole is in turn detoxified by an enzymatic, triphosphopyridine nucleotide-linked reduction to 3-methyloxindole, a nontoxic compound. These enzymatic conversions may be responsible for some of the responses to auxin, particularly sensitivity to its inhibitory effects on growth.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Transhydrogenation in Root Tissue: Mediation by Carbon Dioxide.
I. P. Ting and W. M. Dugger Jr. (1965)
Science 150, 1727-1728
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)