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Science 20 August 1965:
Vol. 149. no. 3686, pp. 876 - 877
DOI: 10.1126/science.149.3686.876
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Articles

Tension Gradients Accompanying Accelerated Oxygen Transport in a Membrane

P. F. Scholander 1

1 Scripps Institution of Oceanography, University of California, San Diego

Facilitated transport of oxygen through hemoglobin has been studied by use of a membrane sandwich of hemoglobin, Teflon, and water. Transport is enhanced only when there is a hemoglobin-bound-02 gradient in the pigment. When passing through a fully oxygenated layer, the accelerated transport is carried by an increased diffusion gradient of oxygen pressure through the solvent. The results substantiate experimentally the diffusion gradients proposed by Zilversmit.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)