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Science 25 June 1965:
Vol. 148. no. 3678, pp. 1743 - 1745
DOI: 10.1126/science.148.3678.1743
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Articles

Degeneration of the Eyes of Tyrosine-Deficient Chick Embryos

C. R. Grau 1, R. E. Austic 1, and G. C. Matteson 1

1 Department of Poultry Husbandry, University of California, Davis

Subjecting 4-day-old chick embryos to a yolk-sac perfusion medium lacking tyrosine resulted in arrest of retinal pigmentation and in degeneration of the neural retina. Phenylaldnine was ineffective in replacing tyrosine. Possibly retinal tyrosinase played a part in initiating the degenerative changes.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)