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Science 4 June 1965:
Vol. 148. no. 3675, pp. 1347 - 1348
DOI: 10.1126/science.148.3675.1347
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Articles

Pancreatic Secretion Induced by Stimulation of the Pyloric Gland Area of the Stomach

R. M. Preshaw 1, A. R. Cooke 1, and M. I. Grossman 1

1 Veterans Administration Center and Departments of Physiology and Medicine, University of California, Los Angeles

Pure gastrin I of Gregory and Tracy stimulated secretion not only of gastric acid but also of pancreatic fluid and protein material. Similarly, endogenous release of gastrin from a transplanted pouch of the pyloric gland area of the stomach, initiated by irrigation with solutions of acetylcholine, stimulated gastric acid secretion and pancreatic flow and protein output in dogs with fistulas of both organs. The effect on the pancreas, like that on the stomach, was inhibited by acidification of the acetylcholine solution.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Gastrin.
M. I. GROSSMAN (1966)
Ann Intern Med 64, 212-216
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