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Science 4 June 1965:
Vol. 148. no. 3675, pp. 1335 - 1336
DOI: 10.1126/science.148.3675.1335
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Articles

Skin Grafts: Delayed Rejection between Pairs of Cattle Twins Showing Erythrocyte Chimerism

W. H. Stone 1, R. G. Cragle 2, E. W. Swanson 2, and D. G. Brown 2

1 Division of Genetics, University of Wisconsin, Madison
2 Agricultural Research Laboratory of the University of Tennessee, Oak Ridge

Although dizygotic cattle twins with erythrocyte chimerism exhibit complete tolerance to each other's hematopoietic tissues exchanged in utero by way of chorionic anastomoses, they may not be completely tolerant to each other's histocompatibility antigens. Skin grafts exchanged between partners of 21 pairs of chimeric twins were rejected by more than half of the twins in an average of 250 days.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
"Intrinsic" Immunological Tolerance in Allophenic Mice.
B. Mintz and W. K. Silvers (1967)
Science 158, 1484-1487
   Abstract »    PDF »
Evidence from Cultured Leucocytes of Blood Cell Chimerism in Ex-Parabiotic Frogs.
E. P. Volpe and B. M. Gebhardt (1966)
Science 154, 1197-1199
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)