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Science 21 May 1965:
Vol. 148. no. 3673, pp. 1097 - 1099
DOI: 10.1126/science.148.3673.1097
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Articles

Tryptamine Oxidation by Extracts of Pea Seedlings: Effect of Growth Retardant beta-Hydroxyethylhydrazine

Donald J. Reed 1

1 Radiation Center, Oregon State University, Corvallis

beta-Hydroxyethylhydrazine forces flowering of pineapple plants, possibly by reducing auxin concentration. A specific and sensitive assay showed that beta-hydroxyethylhydrazine (3.3 x 10-7M) inhibits noncompetitively and almost completely the oxidation of tryptamine to indoleacetaldehyde by extracts of pea-seedling (Pisum sativum L. var. Alaska). The relative rate of oxidation of putrescine to Dgr1-pyrroline compared to that of tryptamine by these extracts and the inhibition of both reactions by beta-hydroxyethylhydrazine suggest that diamine oxidase is inhibited. beta-Hydroxyethylhydrazine is a potent inhibitor in vivo of animal diamine oxidase.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Plant Growth Retardant B-995: A Possible Mode of Action.
D. J. Reed, T. C. Moore, and J. D. Anderson (1965)
Science 148, 1469-1471
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Science. ISSN 0036-8075 (print), 1095-9203 (online)