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Science 26 March 1965:
Vol. 147. no. 3665, p. 1590
DOI: 10.1126/science.147.3665.1590
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Articles

Tricarboxylic Acid Cycle Mutants in Saccharomyces: Comparison of Independently Derived Mutants

M. Ogur 1, A. Roshanmanesh 1, and S. Ogur 1

1 Department of Microbiology and Biological Research Laboratory, Southern Illinois University, Carbondale

A yeast mutant independently isolated as a glutamate auxotroph (glt2-1) was similar to the glt1-1 mutant in exhibiting a blocked tricarboxylic acid cycle due to the lack of aconitate hydratase. The new mutant differed by exhibiting blocks in lysine and cytochrome biosynthesis which segregated together with the glutamate requirement.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)