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Science 26 February 1965:
Vol. 147. no. 3661, pp. 1040 - 1041
DOI: 10.1126/science.147.3661.1040
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Articles

Absence of Taste-Bud Papillae in Familial Dysautonomia

Alfred Smith 1, Alfred Farbman 2, and Joseph Dancis 3

1 Department of Psychiatry, New York University Medical Center, New York
2 Department of Anatomy, Northwestern University Medical School, Chicago, Illinois
3 Department of Pediatrics, New York University Medical Center

No fungiform papillae could be found on the tongues of 30 patients with familial dysautonomia. In ten of these patients a search for vallate papillae was made, but none were found. Inspection of the tongue may thus be useful for diagnosing this rare disease, even in infants. Absence of these sensory receptors suggests that the multiple sensory deficits found in persons with familial dysautonomia may be related to defects in the peripheral receptors.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Unique Hereditary Serisory and Autonomic Neuropathy With Growth Hormone Deficiency.
R. M. Liberfarb, A. H. Jackson, R. D. Eavey, and R. M. Robb (1993)
J Child Neurol 8, 271-276
   Abstract »    PDF »
Congenital Sensory Neuropathies: Diagnostic Distinction From Familial Dysautonomia.
F. B. Axelrod and J. Pearson (1984)
Arch Pediatr Adolesc Med 138, 947-954
   Abstract »    PDF »
Ophthalmologic Studies of Familial Dysautonomia: The Riley-Day Syndrome.
M. F. Goldberg, J. W. Payne, and P. W. Brunt (1968)
Arch Ophthalmol 80, 732-743
   Abstract »    PDF »
Review : Familial Dysautonomia: The Riley-Day Syndrome.
S. P. Ginsberg (1966)
Clinical Pediatrics 5, 308-314
   Abstract »    PDF »
Food Flavor.
L. J. Minor (1966)
Cornell Hospitality Quarterly 7, 69-83
   Abstract »    PDF »
Tongue in Familial Dysautonomia: A Diagnostic Sign.
A. A. SMITH, A. FARBMAN, and J. DANCIS (1965)
Arch Pediatr Adolesc Med 110, 152-153
   Abstract »    PDF »


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