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Science 8 January 1965:
Vol. 147. no. 3654, pp. 167 - 169
DOI: 10.1126/science.147.3654.167
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Articles

Exovagination of Newt Endoderm: Cell Affinities Altered by the Mesodermal Inducing Factor

Ursula Kocher-Becker 1, Heinz Tiedemann 1, and Hildegard Tiedemann 1

1 Carnegie Institution of Washington, Department of Embryology, Baltimore, Maryland, and Heiligenberg-Institut, Heiligenberg/Baden, West Germany

Implantation of a highly purified mesodermal inducing factor in the blastocoel of early gastrulae results in the spreading of endoderm over the ectoderm. The effect can be explained by a change in cell affinities in the ectoderm, initiated by the mesodermal factor.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)