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Science 4 December 1964:
Vol. 146. no. 3649, pp. 1307 - 1309
DOI: 10.1126/science.146.3649.1307
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Articles

Vitamin K Compounds in Bacteria That Are Obligate Anaerobes

Ronald J. Gibbons 1 and Lois P. Engle 1

1 Department of Oral Microbiology, Forsyth Dental Center, Harvard School of Dental Medicine, Boston, Massachusetts

A naphthoquinone-dependent strain of Bacteroides melaninogenicus has been used in a microbiological assay to survey bacteria for compounds of the vitamin K group. Organisms known to contain vitamin K, as well as several bacteria that are obligate anaerobes, produced substances which satisfied the naphthoquinone requirement of the assay organism. Vitamin K was chemically isolated from strains of Bacteroides melaninogenicus, Bacteroides fragilis, and Veillonella alcalescens.


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Role of Feeding and Vitamin K in Hypoprothrombinemia of the Newborn.
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