Tremorine: Its Peripheral Action on Striated Muscle
Bertalan Csillik 1
1 Department of Pharmacology, University of Pennsylvania, Philadelphia 4
Tremorine, injected intraperitoneally into rats, induces the same kind of calcium release in the motor end-plates as that induced by acetylcholine-like agents. Since the same effect results even if the appropriate motor nerve has previously been transected, it is concluded that this myoneural action of Tremorine is not due to a e entral excitation but rather to a peripheral stimulatory property of the drug.