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Science 30 October 1964:
Vol. 146. no. 3644, pp. 653 - 655
DOI: 10.1126/science.146.3644.653
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Articles

DNA Synthesis in Alveolar Cells of the Mammary Gland: Acceleration by Ovarian Hormones

Francesco Bresciani 1

1 Biology Department, Brookhaven National Laboratory, Upton, New York, and Institute of General Pathology, University of Naples, Naples, Italy

In normal alveolar cells of the mammary gland of C3H/HeJ female mice, DNA synthesis lasts an average of 20.7 hours with a coefficient of variation of 26.6 percent. Treatment of the mice with I microgram of 17-beta-estradiol and 1 milligram of progesterone per day for 3 to 4 days decreases the average duration to 10.7 hours and the coefficient of variation to 13.8 percent.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Prevention of Brca1-Mediated Mammary Tumorigenesis in Mice by a Progesterone Antagonist.
A. J. Poole, Y. Li, Y. Kim, S.-C. J. Lin, W.-H. Lee, and E. Y.-H. P. Lee (2006)
Science 314, 1467-1470
   Abstract »    Full Text »    PDF »
Kinetics of Deoxyribonucleic Acid Synthesis within the Inner Enamel Epithelium.
R. E. Stallard, M. A. Diab, and H. A. Zander (1966)
Journal of Dental Research 45, 315-322
   PDF »


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