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Science 10 July 1964:
Vol. 145. no. 3628, pp. 177 - 178
DOI: 10.1126/science.145.3628.177
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Articles

Lethal Alleles in Mus musculus: Local Distribution and Evidence for Isolation of Demes

Paul K. Anderson 1

1 Department of Biology, University of Alberta, Calgary

In the vicinity of Calgary, Alberta, 20.5 percent of wild house mice tested were found to be heterozygous for the lethal allele designated tw5, and an additional 3.4 percent were heterozygous for one or more alleles not belonging to the tw5 group. The distribution patterns of wild-type and lethal alleles within and between clusters of small demes supports the postulate that random drift plays a significant role in the evolution of these populations. Distribution patterns also suggest that the demes are reproductively isolated to a greater degree than has been generally assumed.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Peromyscus: Effect of Early Pairing on Reproduction.
J. L. Hill (1974)
Science 186, 1042-1044
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Gene Flow and Population Differentiation: Studies of clines suggest that differentiation along environmental gradients may be independent of gene flow.
J. A. Endler (1973)
Science 179, 243-250
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Histocompatibility-2 (H-2) Polymorphism in Wild Mice.
J. Klein (1970)
Science 168, 1362-1364
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Mus musculus: Experimental Induction of Territory Formation.
P. K. Anderson and J. L. Hill (1965)
Science 148, 1753-1755
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