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Science 26 June 1964:
Vol. 144. no. 3626, pp. 1578 - 1580
DOI: 10.1126/science.144.3626.1578
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Articles

Amphibian Cell Culture: Permanent Cell Line from the Bullfrog (Rana catesbeiana)

Ken Wolf 1 and M. C. Quimby 1

1 Bureau of Sport Fisheries and Wildlife, Eastern Fish Disease Laboratory, Kearneysville, West Virginia

A line of fibroblast cells has been established from tongue tissue of the bullfrog (Rana catesbeiana). The cells are near-triploid and were subcultured 57 times during the 22/3 years of their existence. Some of their characteristics are described.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Nerve Trophic Function: In vitro Assay of Effects of Nerve Tissue on Muscle Cholinesterase Activity.
T. L. Lentz (1971)
Science 171, 187-189
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Vertebrate Regeneration System: Culture in vitro.
S. B. Simpson Jr. and P. G. Cox (1967)
Science 157, 1330-1332
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