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Science 29 May 1964:
Vol. 144. no. 3622, pp. 1144 - 1147
DOI: 10.1126/science.144.3622.1144
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Articles

Density Gradient Centrifugation of a Murine Leukemia Virus

T. E. O'Connor 1, F. J. Rauscher 1, and R. F. Zeigel 1

1 Laboratory of Viral Oncology, National Cancer Institute, Bethesda, Maryland 20014

The Rauscher leukemia virus separated as a single band upon density gradient centrifugation in cesium chloride, rubidium chloride, sucrose, potassium citrate, or potassium tartrate. Prolonged exposure to concentrated potassium citrate or potassium tartrate solutions caused lysis of the virus; the resulting products, having different densities, separated on the density gradients.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
"C"-Type Viral Particles in Plasma of Cats with Feline Leukemia.
T. G. Kawakami, G. H. Theilen, D. L. Dungworth, R. J. Munn, and S. G. Beall (1967)
Science 158, 1049-1050
   Abstract »    PDF »
Virus-Like Particles in Established Murine Cell Lines: Electron-Microscopic Observations.
D. A. Kindig and W. H. Kirsten (1967)
Science 155, 1543-1545
   Abstract »    PDF »
Viral Etiology of Leukemia: Combined Clinical Staff Conference at the National Institutes of Health.
W. R. BRYAN, J. B. MOLONEY, T. E. O'CONNOR, M. A. FINK, and A. J. DALTON (1965)
Ann Intern Med 62, 376-399
   Abstract »    PDF »
Physical Interaction of a Murine Leukemia Virus with Influenza Virus in vitro.
T. E. O'Connor and F. J. Rauscher (1964)
Science 146, 787-790
   Abstract »    PDF »


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