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Science 22 May 1964:
Vol. 144. no. 3621, pp. 1011 - 1012
DOI: 10.1126/science.144.3621.1011
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Articles

Synthesis of RNA in vitro Stimulated in Dipteran Salivary Glands by 1,1,3-Tricyano-2-Amino-1-Propene

J. Jacob 1 and J. L. Sirlin 1

1 Institute of Animal Genetics, Edinburgh 9, Scotland

1,1,3-Tricyano-2-amino-1-propene stimulates by more than one order of magnitude the incorporation in vitro of uridine into the RNA of dipteran salivary glands. The inhibition by actinomycin D is blocked. Higher doses cause a complete inhibition from which a proportion of the glands recover rapidly upon withdrawal of the substance.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Cretinism in Rats: Enduring Behavioral Deficit Induced by Tricyanoaminopropene.
J. W. Davenport (1970)
Science 167, 1007-1009
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Science. ISSN 0036-8075 (print), 1095-9203 (online)