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Science 3 April 1964:
Vol. 144. no. 3614, pp. 58 - 59
DOI: 10.1126/science.144.3614.58
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Articles

Humoral Factor from the Brain Which Activates Gastric Motility

N. C. Jefferson 1, T. Arai 1, T. Geisel 1, and H. Necheles 1

1 Department of Gastro-Intestinal Research, Michael Reese Hospital and Medical Center, Chicago, Illinois

When the vagus nerves in the neck of the dog are cut and the ends toward the brain are stimulated, gastric contractions follow. These contractions are not abolished by section of the cervical spinal cord, section of anterior and posterior thoracic and lumbar spinal nerves, section of the splanchnic nerves, or paralysis or excision of the celiac plexus. Evidence for the existence of a humoral blood-borne substance originating in the brain was obtained by experiments with an isolated perfused head, by perfusion of isolated stomachs by donor dogs, by cross-perfusion between two dogs, and by plasmapheresis. stimulates the stomach.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Action of Reserpine on Gastric Secretion.
H. Schapiro (1967)
Arch Surg 95, 144-150
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